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Vaccination study CoVaKo 2021 - Recording of vaccination side effects

What is CoVaKo all about?

Regulatory studies demonstrate the efficacy and safety of COVID vaccines. The current task is to investigate whether the results can be replicated under everyday conditions. These questions have a high urgency, as vaccination is to be offered to millions of people within a very short time. In order to obtain a reliable assessment of the side effects of the COVID vaccination, comparative data from other vaccinations (influenza, pneumococcus or shingles) should also be considered. Within the framework of this study, the Institute of General Medicine is concerned with the active recording of side effects of various vaccinations. The focus is on adverse events that led to medical care, medication or inability to work.

In participating vaccination centers as well as in general practitioner and specialist practices, vaccinated individuals receive a handout immediately after vaccination together with the vaccination certificate, on which the link/QR code to the survey page can be found.


On December 2021: Presentation of results by Minister Siebler. (Link)

On 16.4.2021 the registration for participation in the survey on vaccination side effects ends. In the coming weeks, we will then turn our attention to the data analysis. As soon as results are available, we will inform you on our website.

Warkentin L, Hueber S, Deiters B, Klohn F, Kühlein T. Vitamin-K-antagonist phenprocoumon versus low-dose direct oral anticoagulants (DOACs) in patients with atrial fibrillation: a real-world analysis of German claims data. Thromb J. 2022;20(1):31. DOI:10.1186/s12959-022-00389-9 - Link

Warkentin L, Zeschick N, Kühlein T, Steininger P, Überla K, Kaiser I, Gall C, Sebastião M, Hueber S. Reactogenicity after heterologous and homologous COVID-19 prime-boost vaccination regimens: descriptive interim results of a comparative observational cohort study. BMC Infectious Diseases. 2022;22(1):504. DOI:10.1186/s12879-022-07443-x - Link

Zeschick N, Warkentin L, Kühlein T, Steininger P, Überla K, Hueber S, Sebastião M. Active monitoring of adverse reactions following COVID-19 and other vaccinations: a feasibility study as part of the CoVaKo project. Pilot and Feasibility Studies. 2022;8(1):134. DOI:10.1186/s40814-022-01088-y - Link