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Development of the S3-Guideline "Thyroid Nodules in Adults. Recommendations on prevention, diagnosis and therapy in primary care.

About half of the adults in Germany have at least one thyroid nodule. These are mostly benign and have no need for treatment. Identifying the few hazardous progressions is a challenge for primary care physicians. They need to know when a thyroid nodule might require treatment. Also, any subsequent care that may be required by other specialties must be well coordinated. However, a guideline does not exist.

The aim of the project is to develop a new S3 guideline on the prevention, diagnostic and therapy of thyroid nodules, which is primarily intended to support primary care. In the first step, the clinically relevant key questions of the guideline will be agreed upon. This is followed by a systematic evidence search and evaluation. Based on this, recommendations are formulated and a first long version of the guideline is drafted. From this, a short version of the guideline and a patient guideline will be developed, which will then be tested in 20 GP practices.


  • Consortium leadership: Bereich Allgemeinmedizin Medizinische Fakultät Carl Gustav Carus an der Technischen Universität Dresden
  • Abteilung Allgemeinmedizin, Universitätsmedizin Greifswald
  • Institut für Allgemeinmedizin am Universitätsklinikum Würzburg
  • Institut für Allgemeinmedizin an der Goethe Universität Frankfurt am Main
  • Deutsche Gesellschaft für Allgemeinmedizin und Familienmedizin e. V.

The project is funded by Federal Joint Committee G-BA for three years with a total of about 315.000 euros.